L-778123 hydrochloride

CAS No. 253863-00-2

L-778123 hydrochloride( L-778,123 hydrochloride )

Catalog No. M17457 CAS No. 253863-00-2

The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 34 In Stock
5MG 55 In Stock
10MG 80 In Stock
25MG 143 In Stock
50MG 236 In Stock
100MG 398 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    L-778123 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
  • Description
    The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    L-778,123 hydrochloride
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    Farnesyl transferase (FTase)
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    253863-00-2
  • Formula Weight
    442.34
  • Molecular Formula
    C22H21Cl2N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 25 mg/mL; 56.52 mM
  • SMILES
    c1cc(cc(c1)N1CCN(Cc2cncn2Cc2ccc(cc2)C#N)CC1=O)Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lobell RB, et al. Mol Y Ther. 2002 Jul;1(9):747-58.
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