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L-778123 hydrochloride

CAS No. 253863-00-2

L-778123 hydrochloride( L-778,123 hydrochloride )

Catalog No. M17457 CAS No. 253863-00-2

The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    L-778123 hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
  • Description
    The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    L-778,123 hydrochloride
  • Pathway
    Endocrinology/Hormones
  • Target
    Estrogen Receptor/ERR
  • Recptor
    Farnesyl transferase (FTase)
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    253863-00-2
  • Formula Weight
    442.34
  • Molecular Formula
    C22H21Cl2N5O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : ≥ 25 mg/mL; 56.52 mM
  • SMILES
    c1cc(cc(c1)N1CCN(Cc2cncn2Cc2ccc(cc2)C#N)CC1=O)Cl.Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lobell RB, et al. Mol Y Ther. 2002 Jul;1(9):747-58.
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